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Exploration of analysis methods for diagnostic imaging tests: problems with ROC AUC and confidence scores in CT colonography

Abstract:

Background Different methods of evaluating diagnostic performance when comparing diagnostic tests may lead to different results. We compared two such approaches, sensitivity and specificity with area under the Receiver Operating Characteristic Curve (ROC AUC) for the evaluation of CT colonography for the detection of polyps, either with or without computer assisted detection. Methods In a multireader multicase study of 10 readers and 107 cases we compared sensitivity and specificity, using ra...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0107633

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS ONE Journal website
Volume:
9
Issue:
10
Pages:
ARTN e107633
Publication date:
2014-10-29
Acceptance date:
2014-08-19
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Language:
English
Keywords:
UUID:
uuid:6ec68b59-866a-4265-8a76-9a10a0e5eed5
Local pid:
pubs:488448
Source identifiers:
488448
Deposit date:
2014-11-09

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