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Exploring single-molecule dynamics with fluorescence nanoscopy

Abstract:

The study of molecular dynamics at the single-molecule level with fluorescence correlation spectroscopy (FCS) and far-field optics has contributed greatly to the functional understanding of complex systems. Unfortunately, such studies are restricted to length scales of >200 nm because diffraction does not allow further reduction of the measurement volume. This sets an upper limit on the applicable concentration of fluorescently labeled molecules and even more importantly, averages out deta...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1088/1367-2630/11/10/103054

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Publisher:
IOP Publishing
Journal:
New Journal of Physics More from this journal
Volume:
11
Issue:
10
Article number:
103054
Publication date:
2009-10-27
DOI:
EISSN:
1367-2630
ISSN:
1367-2630
UUID:
uuid:6ec07533-21a5-4e16-b28e-e427aeaf8228
Local pid:
pubs:222249
Source identifiers:
222249
Deposit date:
2012-12-19

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