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Journal article

Diseases associated with the extracellular calcium-sensing receptor.

Abstract:

The human calcium-sensing receptor (CaSR) is a 1078 amino acid cell surface protein, which is predominantly expressed in the parathyroids and kidney, and is a member of the family of G protein-coupled receptors. The CaSR allows regulation of parathyroid hormone (PTH) secretion and renal tubular calcium reabsorption in response to alterations in extracellular calcium concentrations. The human CaSR gene is located on chromosome 3q21.1 and loss-of-function CaSR mutations have been reported in th...

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Publication status:
Published

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Publisher copy:
10.1016/j.ceca.2003.10.010

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
Journal:
Cell calcium More from this journal
Volume:
35
Issue:
3
Pages:
275-282
Publication date:
2004-03-01
DOI:
EISSN:
1532-1991
ISSN:
0143-4160
Language:
English
Keywords:
Pubs id:
pubs:6739
UUID:
uuid:6eb9dea2-b647-41ce-aef4-50af7ce07b8c
Local pid:
pubs:6739
Source identifiers:
6739
Deposit date:
2012-12-19

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