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Predicting beta bursts from local field potentials to improve closed-loop DBS paradigms in Parkinson's patients

Abstract:

Motor symptoms in Parkinson's disease (PD) correlate with an excess in synchrony in the beta frequency band (13-30Hz) of local field potentials recorded from basal ganglia circuits. Recent results have suggested that this abnormal activity arises as a result of changes in specific dynamical features of the underlying neural signatures. In particular, patterns of activity in the beta band have been shown to be structured in bursts of longer durations and higher amplitudes in untreated patients...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1109/EMBC.2018.8513348

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Agrawal, M More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Oxford college:
All Souls College
Swiss Parkinson Association More from this funder
Publisher:
Institute of Electrical and Electronics Engineers Publisher's website
Publication date:
2018-10-29
Acceptance date:
2018-06-04
DOI:
Pubs id:
pubs:854771
URN:
uri:6e87d2de-3490-4156-ad14-1579ba399cf9
UUID:
uuid:6e87d2de-3490-4156-ad14-1579ba399cf9
Local pid:
pubs:854771

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