Journal article icon

Journal article

IL‐33 drives the production of mouse regulatory T cells with enhanced in vivo suppressive activity in skin transplantation

Abstract:

Regulatory T cells (Tregs) are crucial mediators of immune homeostasis with the ability to modulate allogeneic response and control transplant rejection. While Treg‐based cell therapies have shown immense promise, methods to optimize current strategies are critical for successful implementation within the clinic. IL‐33 is a cytokine with pleiotropic properties and effects on Treg function and development. In this study we explored the unique properties of Treg populations activated through th...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1111/ajt.16266

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Oxford college:
Exeter College
Role:
Author
ORCID:
0000-0002-8279-7732
More from this funder
Name:
Wellcome Trust
Grant:
211122/Z/18/Z
More from this funder
Name:
National Institute for Health Research
Grant:
CL-2013-13-005
Publisher:
Wiley
Journal:
American Journal of Transplantation More from this journal
Volume:
21
Issue:
3
Pages:
978-992
Publication date:
2020-08-16
Acceptance date:
2020-08-08
DOI:
EISSN:
1600-6143
ISSN:
1600-6135
Language:
English
Keywords:
Pubs id:
1126113
Local pid:
pubs:1126113
Deposit date:
2020-08-14

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP