- Abstract:
-
Acute tryptophan depletion (ATD) induces depressive symptoms in 50-60% of selective serotonin reuptake inhibitor (SSRI) treated, recovered depressed patients. However, no reliable predictors of mood response to ATD have been established. In the present study, individual subject data of six ATD studies were pooled ('mega-analysis') in order to investigate the mediating role of clinical, demographic and biochemical characteristics in the mood response to ATD. A procedure was developed to make d...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/s0893-133x(02)00361-5
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- Journal:
- Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
- Volume:
- 27
- Issue:
- 5
- Pages:
- 852-861
- Publication date:
- 2002-11-05
- DOI:
- EISSN:
-
1740-634X
- ISSN:
-
0893-133X
- URN:
-
uuid:6e6d389d-0751-4a31-8699-d7de82322f7d
- Source identifiers:
-
185865
- Local pid:
- pubs:185865
- Copyright date:
- 2002
Journal article
Predictors of mood response to acute tryptophan depletion. A reanalysis.
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