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Cellular mechanisms of bone resorption in breast carcinoma.

Abstract:

The cellular mechanisms that account for the increase in osteoclast numbers and bone resorption in skeletal breast cancer metastasis are unclear. Osteoclasts are marrow-derived cells which form by fusion of mononuclear phagocyte precursors that circulate in the monocyte fraction. In this study we have determined whether circulating osteoclast precursors are increased in number or have an increased sensitivity to humoral factors for osteoclastogenesis in breast cancer patients with skeletal me...

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Publication status:
Published

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Publisher copy:
10.1054/bjoc.2001.1856

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
British journal of cancer More from this journal
Volume:
85
Issue:
1
Pages:
78-84
Publication date:
2001-07-01
DOI:
EISSN:
1532-1827
ISSN:
0007-0920

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