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Apolipoprotein A-I breakdown is induced by thrombolysis in coronary patients.

Abstract:

BACKGROUND: The outcome of percutaneous coronary intervention (PCI) is apparently worse in patients receiving a prior thrombolytic therapy ('facilitated PCI'). Recombinant tissue-type plasminogen activator (rt-PA) can degrade circulating high-density lipoproteins (HDL) bound apolipoprotein A-I (apoA-I), thus possibly reducing the vascular protective activity. There have never been reports of the detection of apolipoprotein breakdown products in the circulation. AIM: We studied the potential ...

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Publication status:
Published

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Publisher copy:
10.1080/07853890701288760

Authors


Journal:
Annals of medicine More from this journal
Volume:
39
Issue:
4
Pages:
306-311
Publication date:
2007-01-01
DOI:
EISSN:
1365-2060
ISSN:
0785-3890
Language:
English
Keywords:
Pubs id:
pubs:228795
UUID:
uuid:6e61c699-f0a3-445b-815d-ade46fe415a5
Local pid:
pubs:228795
Source identifiers:
228795
Deposit date:
2013-11-16

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