Trial protocol: rapid reduction versus abrupt quitting for smokers who want to stop soon: a randomised controlled non-inferiority trial
The standard way to stop smoking is to stop abruptly on a quit day with no prior reduction in consumption of cigarettes. Many smokers feel that reduction is natural and if reduction programmes were offered, many more might take up treatment. Few trials of reduction versus abrupt cessation have been completed. Most are small, do not use pharmacotherapy, and do not meet the standards necessary to obtain a marketing authorisation for a pharmacotherapy.
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© 2009 Lindson et al; licensee BioMed Central Ltd.
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