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Combined chloroquine, sulfadoxine/pyrimethamine and primaquine against Plasmodium falciparum in Central Java, Indonesia.

Abstract:

BACKGROUND: Chloroquine (CQ) or sulfadoxine-pyrimethamine (SP) monotherapy for Plasmodium falciparum often leads to therapeutic failure in Indonesia. Combining CQ with other drugs, like SP, may provide an affordable, available and effective option where artemisinin-combined therapies (ACT) are not licensed or are unavailable. METHODS: This study compared CQ (n = 29 subjects) versus CQ + SP (with or without primaquine; n = 88) for clinical and parasitological cure of uncomplicated falciparum ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1475-2875-5-108

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Name:
Global Emerging Infections Surveillance and Response System
Publisher:
BioMed Central
Journal:
Malaria Journal More from this journal
Volume:
5
Article number:
108
Publication date:
2006-01-01
DOI:
EISSN:
1475-2875
ISSN:
1475-2875
Language:
English
Keywords:
UUID:
uuid:6e57945e-c87b-4957-97bb-c8cf6afcf699
Local pid:
pubs:81715
Source identifiers:
81715
Deposit date:
2012-12-19

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