Journal article icon

Journal article

Downstage migration after neoadjuvant chemoradiotherapy for rectal cancer: The reverse of the Will Rogers phenomenon?

Abstract:

© 2015 American Cancer Society. Downstaging after neoadjuvant treatment is increasingly used as a prognostic factor and surrogate endpoint in clinical trials. However, in recent trials of neoadjuvant 5-fluorouracil-based chemoradiotherapy for rectal cancer, downstaging did not translate into a benefit with regard to either disease-free survival (DFS) or overall survival. By analyzing the 10-year outcome data of the German CAO/ARO/AIO-94 phase 3 trial, the authors demonstrated that significant...

Expand abstract

Actions


Access Document


Publisher copy:
10.1002/cncr.29260

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Liersch, T More by this author
Fietkau, R More by this author
Hohenberger, W More by this author
Expand authors...
Journal:
Cancer
Volume:
121
Issue:
11
Pages:
1724-1727
Publication date:
2015
DOI:
EISSN:
1097-0142
ISSN:
0008-543X
URN:
uuid:6e4cca1c-2cb5-4222-a790-f3515a4bd2be
Source identifiers:
526438
Local pid:
pubs:526438

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP