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The structure of a reduced form of OxyR from Neisseria meningitidis

Abstract:

Background: Survival of the human pathogen, Neisseria meningitidis, requires an effective response to oxidative stress resulting from the release of hydrogen peroxide by cells of the human immune system. In N. meningitidis, expression of catalase, which is responsible for detoxifying hydrogen peroxide, is controlled by OxyR, a redox responsive LysR-type regulator. OxyR responds directly to intracellular hydrogen peroxide through the reversible formation...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1472-6807-10-10

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Institution:
University of Oxford
Department:
MSD, Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Department:
MSD, Clinical Medicine, Structural Biology
Role:
Author
Publisher:
BioMed Central
Journal:
BMC Structural Biology More from this journal
Volume:
10
Issue:
1
Pages:
10
Publication date:
2010-05-17
Acceptance date:
2010-05-17
DOI:
EISSN:
1472-6807
Language:
English
Keywords:
UUID:
uuid:6e4699d3-0779-4058-bcc8-a04eeeaf616a
Local pid:
pubs:60440
Source identifiers:
60440
Deposit date:
2012-12-19

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