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A near-infrared fluorescent probe for sensitive detection and imaging of sulfane sulfur in living cells and in vivo

Abstract:

Sulfane sulfur refers to ionized sulfur that is reversibly attached to other sulfur atoms in the form of 6-valence electrons (S0). Sulfane sulfur possesses stronger nucleophilicity and reducibility than hydrogen sulfide in a series of physiological reactions, which probably makes sulfane sulfur the actual signal molecule in cells. Herein, we designed and synthesized a near-infrared (NIR) fluorescent probe BD-diSH for sensitive detection and imaging of sulfane sulfur in living cells and in viv...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1039/c7bm00951h

Authors


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Division:
MSD
Department:
NDM
Sub department:
Oxford Ludwig Institute
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Oxford Ludwig Institute
Role:
Author
More by this author
Role:
Author
ORCID:
0000-0003-0073-6299
More by this author
Role:
Author
ORCID:
0000-0002-3764-3515
Publisher:
Royal Society of Chemistry Publisher's website
Journal:
Biomaterials Science Journal website
Volume:
6
Issue:
3
Pages:
672-682
Publication date:
2018-01-30
Acceptance date:
2018-01-28
DOI:
EISSN:
2047-4849
ISSN:
2047-4830
Language:
English
Keywords:
Pubs id:
1103977
Local pid:
pubs:1103977
Deposit date:
2020-05-11

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