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FTO genetic variants and risk of obesity and type 2 diabetes: a meta-analysis of 28,394 Indians.

Abstract:

OBJECTIVE: To investigate the magnitude of association of FTO variants with obesity, type 2 diabetes (T2DM), and related traits among Asian Indians. METHODS: Random-effect meta-analysis was performed on pooled data from eight studies (n = 28,394) for obesity and related traits and six studies (n = 24,987) for assessment of T2DM risk in Indians where FTO variants were reported. RESULTS: The minor A-allele of the FTO variant rs9939609 was associated with increased risk of obesity (OR 1.15, 95% ...

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Publication status:
Published

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Publisher copy:
10.1002/oby.20606

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM, Biomedical Research Centre
Brismar, K More by this author
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Journal:
Obesity (Silver Spring, Md.)
Volume:
22
Issue:
3
Pages:
964-970
Publication date:
2014-03-05
DOI:
EISSN:
1930-739X
ISSN:
1930-7381
URN:
uuid:6e28d0bf-392d-46d0-ab1e-252ced7fb944
Source identifiers:
418528
Local pid:
pubs:418528

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