FTO genetic variants and risk of obesity and type 2 diabetes: a meta-analysis of 28,394 Indians.
OBJECTIVE: To investigate the magnitude of association of FTO variants with obesity, type 2 diabetes (T2DM), and related traits among Asian Indians. METHODS: Random-effect meta-analysis was performed on pooled data from eight studies (n = 28,394) for obesity and related traits and six studies (n = 24,987) for assessment of T2DM risk in Indians where FTO variants were reported. RESULTS: The minor A-allele of the FTO variant rs9939609 was associated with increased risk of obesity (OR 1.15, 95% ...Expand abstract
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