Journal article
Cyclin-dependent kinase inhibitor p27Kip1 expression and interaction with other cell cycle-associated proteins in mammary carcinoma.
- Abstract:
-
p27, cyclin D1, and retinoblastoma (Rb) protein have been demonstrated using immunohistochemistry in 189 cases of primary breast carcinoma with long-term follow-up. There was a statistically significant association between the expression of p27 and both cyclin D1 and the retinoblastoma gene product (pRb), corresponding to their close interactions in regulating the G1/S transition in the cell cycle. Low levels of p27 were seen in high-grade, rapidly proliferating, oestrogen receptor-negative t...
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- Publication status:
- Published
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- Publisher copy:
- 10.1002/(sici)1096-9896(199901)187:2<200::aid-path228>3.0.co;2-m
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Authors
Bibliographic Details
- Journal:
- Journal of pathology
- Volume:
- 187
- Issue:
- 2
- Pages:
- 200-206
- Publication date:
- 1999-01-01
- DOI:
- EISSN:
-
1096-9896
- ISSN:
-
0022-3417
- Source identifiers:
-
83935
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:83935
- UUID:
-
uuid:6e016fd9-c5b8-4bc4-b536-f44dbd6d0aaa
- Local pid:
- pubs:83935
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 1999
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