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Effect of glyceryl trinitrate on hemodynamics in acute stroke

Abstract:

Background and Purpose- Increased blood pressure (BP), heart rate, and their derivatives (variability, pulse pressure, rate-pressure product) are associated with poor clinical outcome in acute stroke. We assessed the effects of glyceryl trinitrate (GTN) on hemodynamic parameters and these on outcome in participants in the ENOS trial (Efficacy of Nitric Oxide in Stroke). Methods- Four thousand and eleven patients with acute stroke and raised BP were randomized within 48 hours of onset to trans...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1161/STROKEAHA.118.023190

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Publisher:
American Heart Association Publisher's website
Journal:
Stroke Journal website
Volume:
50
Issue:
2019
Pages:
405-412
Publication date:
2019-01-10
Acceptance date:
2018-11-13
DOI:
EISSN:
1524-4628
ISSN:
0039-2499
Pubs id:
pubs:959137
URN:
uri:6e00fa04-d52e-412a-8e90-276977795fc0
UUID:
uuid:6e00fa04-d52e-412a-8e90-276977795fc0
Local pid:
pubs:959137

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