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Cross-sectional analysis of abnormalities of mineral homeostasis, vitamin D and parathyroid hormone in a cohort of pre-dialysis patients. The chronic renal impairment in Birmingham (CRIB) study.

Abstract:

BACKGROUND: Disturbances in mineral and vitamin D metabolism, which affect parathyroid hormone (PTH) synthesis, are well recognized in patients receiving dialysis. However, it is unclear at what stage of chronic kidney disease (CKD) these abnormalities develop. METHODS: The associations between CKD stages 3 and 5, and alterations of calcium, phosphate, vitamin D and PTH concentrations were assessed in 249 patients (mean age 61 years, 66% male) and 79 age- and sex-matched healthy controls. RES...

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Publication status:
Published

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Publisher copy:
10.1159/000108652

Authors


Zehnder, D More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit, BHF Centre of Research Excellence
Wheeler, DC More by this author
Blackwell, L More by this author
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Journal:
Nephron. Clinical practice
Volume:
107
Issue:
3
Pages:
c109-c116
Publication date:
2007
DOI:
EISSN:
1660-2110
ISSN:
1660-8151
URN:
uuid:6dff8b76-41c9-4d58-9c7a-0a276cb7023c
Source identifiers:
33984
Local pid:
pubs:33984

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