Journal article
Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain.
- Abstract:
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Forkhead-box protein P2 is a transcription factor that has been associated with intriguing aspects of cognitive function in humans, non-human mammals, and song-learning birds. Heterozygous mutations of the human FOXP2 gene cause a monogenic speech and language disorder. Reduced functional dosage of the mouse version (Foxp2) causes deficient cortico-striatal synaptic plasticity and impairs motor-skill learning. Moreover, the songbird orthologue appears critically important for vocal learning. ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.8MB)
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- Publisher copy:
- 10.1371/journal.pgen.1002145
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Authors
Funding
+ Christopher Welch Biological Sciences Scholarship
More from this funder
Funding agency for:
Vernes, S
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Genetics Journal website
- Volume:
- 7
- Issue:
- 7
- Article number:
- e1002145
- Publication date:
- 2011-07-01
- DOI:
- EISSN:
-
1553-7404
- ISSN:
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1553-7390
- Source identifiers:
-
166453
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:6dfc4adb-1078-401f-ad1b-2d1055b31a96
- Local pid:
- pubs:166453
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Vernes et al
- Copyright date:
- 2011
- Notes:
- Copyright 2011 Vernes et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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