Journal article
Particle-based multiscale modeling of calcium puff dynamics
- Abstract:
-
Intracellular calcium is regulated in part by the release of Ca2+ ions from the endoplasmic reticulum via inositol-4,5-triphosphate receptor (IP3R) channels (among other possibilities such as RyR and L-type calcium channels). The resulting dynamics are highly diverse, lead to local calcium “pu↵s” as well as global waves propagating through cells, as observed in Xenopus oocytes, neurons, and other cell types. Local fluctuations in the number of calcium ions play a crucial role in the onset of ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Bibliographic Details
- Publisher:
- Society for Industrial and Applied Mathematics Publisher's website
- Journal:
- Multiscale Modeling and Simulation Journal website
- Publication date:
- 2016-07-21
- Acceptance date:
- 2016-04-08
- DOI:
- EISSN:
-
1540-3467
- ISSN:
-
1540-3459
Item Description
- Keywords:
- Pubs id:
-
pubs:615195
- UUID:
-
uuid:6de274c1-6843-46f7-8204-b19cfa72dbe9
- Local pid:
- pubs:615195
- Source identifiers:
-
615195
- Deposit date:
- 2016-04-14
Terms of use
- Copyright holder:
- Society for Industrial and Applied Mathematics
- Copyright date:
- 2016
- Notes:
- © 2016 Society for Industrial and Applied Mathematics. Published by SIAM under the terms of the Creative Commons 4.0 license.
- Licence:
- CC Attribution (CC BY)
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