Journal article icon

Journal article

Subthalamic and nigral neurons are differentially modulated during parkinsonian gait

Abstract:

The parkinsonian gait disorder and freezing of gait are therapeutically demanding symptoms with considerable impact on quality of life. The aim of this study was to assess the role of subthalamic and nigral neurons in the parkinsonian gait control using intraoperative microelectrode recordings of basal ganglia neurons during a supine stepping task. Twelve male patients (56 ± 7 years) suffering from moderate idiopathic Parkinson's disease (disease duration 10 ± 3 years, Hoehn and Yahr stage 2)...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1093/brain/awad006

Authors


Publisher:
Oxford University Press
Journal:
Brain More from this journal
Volume:
146
Issue:
7
Pages:
2766-2779
Publication date:
2023-02-02
Acceptance date:
2022-12-22
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
Pmid:
36730026
Language:
English
Keywords:
Pubs id:
1328531
Local pid:
pubs:1328531
Deposit date:
2023-11-03

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP