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Persistence of bactericidal antibodies following infant serogroup B meningococcal immunization (4CMenB) and booster dose response at 12, 18 or 24 months of age

Abstract:
Background: A serogroup B meningococcal vaccine (4CMenB) is licensed for infant use in countries including Canada, Australia and those of the European Union. Data on serum bactericidal antibody (hSBA) waning and the ideal timing of a ‘toddler’ booster dose are essential to optimise vaccine utilization. Methods: An open-labeled, multicenter phase-2b follow-on European study conducted from 2009 to 2012. Participants previously receiving 4CMenB with routine vacc... Expand abstract
Publication status:
Accepted
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
Novartis Vaccines and Diagnostics More from this funder
Publisher:
Lippincott, Williams and Wilkins Publisher's website
Journal:
Pediatric Infectious Disease Journal Journal website
Publication date:
2015-01-01
DOI:
ISSN:
1532-0987
Pubs id:
pubs:574337
UUID:
uuid:6dc5c441-f1a6-410c-8de9-fcd457da57b2
Local pid:
pubs:574337
Source identifiers:
574337
Deposit date:
2015-11-17

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