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An investigation of the effects of electroconvulsive shock on mesolimbic dopamine and amino acid transmitter system

Abstract:

Electroconvulsive therapy (ECT) is an effective, yet controversial, treatment of major depressive illness, though its mechanism of action is not known. Several areas of research suggest a key role of the mesolimbic system, and the nucleus accumbens in particular, in the antidepressant effects of ECT. Anatomical, biochemical and behavioural evidence indicates that dopamine, GABA and glutamate neurotransmitter systems interact in the ac...

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Institution:
University of Oxford
Division:
MSD
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Publication date:
1995
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Subjects:
UUID:
uuid:6dc583e0-cb02-4550-87cb-195ac4264f3e
Local pid:
td:602835181
Source identifiers:
602835181
Deposit date:
2013-01-18

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