Journal article
RNA sequencing (RNA-Seq) reveals extremely low levels of reticulocyte-derived globin gene transcripts in peripheral blood from horses (Equus caballus) and cattle (Bos taurus)
- Abstract:
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RNA-seq has emerged as an important technology for measuring gene expression in peripheral blood samples collected from humans and other vertebrate species. In particular, transcriptomics analyses of whole blood can be used to study immunobiology and develop novel biomarkers of infectious disease. However, an obstacle to these methods in many mammalian species is the presence of reticulocyte-derived globin mRNAs in large quantities, which can complicate RNA-seq library sequencing and impede d...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.9MB)
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- Publisher copy:
- 10.3389/fgene.2018.00278
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Authors
Funding
+ Department of Agriculture, Food and the Marine
More from this funder
Grant:
Research Stimulus Grant (RSF 06 405
Bibliographic Details
- Publisher:
- Frontiers Media Publisher's website
- Journal:
- Frontiers in Genetics Journal website
- Volume:
- 9
- Issue:
- AUG
- Article number:
- 278
- Publication date:
- 2018-08-14
- Acceptance date:
- 2018-07-09
- DOI:
- EISSN:
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1664-8021
- Pmid:
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30154823
- Source identifiers:
-
911118
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:911118
- UUID:
-
uuid:6dc30b5e-d444-461c-89f1-cb41d3fe1e6c
- Local pid:
- pubs:911118
- Deposit date:
- 2018-11-12
Terms of use
- Copyright holder:
- Correia et al
- Copyright date:
- 2018
- Notes:
- Copyright © 2018 Correia et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
- Licence:
- CC Attribution (CC BY)
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