Journal article
Oxaliplatin and [Pt(R,R-DACH)(panobinostat-2H)] show nanomolar cytotoxicity towards diffuse intrinsic pontine glioma (DIPG)
- Abstract:
-
We report the synthesis of two novel platinum(II) complexes which incorporate histone deacetylase (HDAC) inhibitors: [PtII(R,R-DACH)(Sub-H)] (1), [PtII(R,R-DACH)(panobinostat-2H)] (2), where SubH = suberoyl-bis-hydroxamic acid; DACH = (1R,2R)-(–)-1,2-diaminocyclohexane and panobin...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- Royal Society of Chemistry Publisher's website
- Journal:
- Dalton Transactions Journal website
- Volume:
- 49
- Issue:
- 17
- Pages:
- 5703-5710
- Publication date:
- 2020-04-16
- Acceptance date:
- 2020-03-26
- DOI:
- EISSN:
-
1477-9234
- ISSN:
-
1477-9226
- Pmid:
-
32297619
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1101179
- Local pid:
- pubs:1101179
- Deposit date:
- 2020-07-21
Terms of use
- Copyright holder:
- The Royal Society of Chemistry
- Copyright date:
- 2020
- Rights statement:
- © The Royal Society of Chemistry 2020. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence
- Licence:
- CC Attribution (CC BY)
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