A group is known as `large' if some finite index subgroup admits a surjective homomorphism onto a non-abelian free group. The main theorem of the paper is as follows. Let G be a finitely generated, large group and let g_1,...,g_r be a collection of elements of G. Then G/<> is also large, for infinitely many integers n. Furthermore, when G is free, this holds for all but finitely many n. These results have the following application to Dehn surgery. Let M be a compact ori...