Management of prostate cancer. Part 1: chemoprevention.

Journal article

Numerous agents have been investigated in prostate cancer prevention. Many manipulate sex steroid levels or function, some regulate response to oxidative stress and others affect tumor proliferation and/or apoptosis. Some are postulated to even affect downstream targets, such as cyclooxygenase-2, which has been shown to be elevated in prostate cancer by most investigators. The evidence for all these potential chemopreventive agents is critically reviewed. While the current information base is...

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Authors: Sooriakumaran, P

• Journal: Expert review of anticancer therapy
• Volume: 6
• Issue: 3
• Pages: 419-425
• Publication date: 2006-03-01
• DOI: 10.1586/14737140.6.3.419
• EISSN: 1744-8328
• ISSN: 1473-7140
• Language: English
• Keywords: Humans; Chemoprevention; Prostatic Neoplasms; Dietary Fats; Clinical Trials as Topic; Gonadal Steroid Hormones; Cell Proliferation; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Male