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Immunologic and functional consequences of chemical (tetrachlorophthalic anhydride)-induced asthma after four years of avoidance of exposure.

Abstract:

Seven patients with occupational asthma caused by a chemical, tetrachlorophthalic anhydride (TCPA), left their work in 1980. They have subsequently avoided TCPA exposure and have been followed until 1985. One patient died in 1981. The six living patients reported continuing symptoms suggestive of asthma, and five who were studied in 1985 demonstrated mild bronchial hyperresponsiveness (histamine concentration provoking a 20% fall in FEV1 range 2.7 to 12.5 mg/ml). Specific IgE antibody to TCPA...

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Institution:
University of Oxford
Department:
Oxford, MSD, Population Health
Topping, MD More by this author
Newman Taylor, AJ More by this author
Journal:
The Journal of allergy and clinical immunology
Volume:
80
Issue:
2
Pages:
212-218
Publication date:
1987-08-05
DOI:
EISSN:
1097-6825
ISSN:
0091-6749
URN:
uuid:6d9d2152-5ca2-4153-bd91-29190af8fa5e
Source identifiers:
245625
Local pid:
pubs:245625

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