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Journal article

Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials

Abstract:

Background Postmastectomy radiotherapy was shown in previous meta-analyses to reduce the risks of both recurrence and breast cancer mortality in all women with node-positive disease considered together. However, the benefit in women with only one to three positive lymph nodes is uncertain. We aimed to assess the effect of radiotherapy in these women after mastectomy and axillary dissection.

Methods We did a meta-analysis of individual data for 8135...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/S0140-6736(14)60488-8

Authors


More by this author
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Contributor
Role:
Contributor
Role:
Contributor
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Contributor
Role:
Contributor
Publisher:
Elsevier
Journal:
Lancet More from this journal
Volume:
383
Issue:
9935
Pages:
2127-2135
Publication date:
2014-03-19
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
Language:
English
UUID:
uuid:6d9697ef-2fa3-4b93-8725-1c2f188a3741
Local pid:
pubs:471188
Source identifiers:
471188
Deposit date:
2014-07-11

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