Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials.
Postmastectomy radiotherapy was shown in previous meta-analyses to reduce the risks of both recurrence and breast cancer mortality in all women with node-positive disease considered together. However, the benefit in women with only one to three positive lymph nodes is uncertain. We aimed to assess the effect of radiotherapy in these women after mastectomy and axillary dissection.We did a meta-analysis of individual data for 8135 women randomly assigned to treatment groups during 1964-86 in 22...Expand abstract
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articletitle: Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials
journaltitle: The Lancet
copyright: Copyright © 2014 EBCTCG. Open Access article distributed under the terms of CC BY. Published by Elsevier Ltd. Copyright © EBCTCG. Open Access article distributed under the terms of CC BY. Open Access funded by Cancer Research UK.
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