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Impact of guidelines and enhanced antibiotic stewardship on reducing broad-spectrum antibiotic usage and its effect on incidence of Clostridium difficile infection

Abstract:

Objectives: To evaluate the impact of an 'intervention' consisting of revised antibiotic guidelines for empirical treatment of common infections and enhanced stewardship on reducing broad-spectrum antibiotic usage and its effect on incidence of Clostridium difficile infection (CDI). Methods: This was a retrospective, quasi-experimental study using interrupted time series (ITS) over 12 months before and after the intervention. The setting was adult medical and surgical wards in University Hosp...

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Publisher copy:
10.1093/jac/dkr253

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Journal:
Journal of Antimicrobial Chemotherapy
Volume:
66
Issue:
9
Pages:
2168-2174
Publication date:
2011-09-05
DOI:
EISSN:
1460-2091
ISSN:
0305-7453
URN:
uuid:6d95333a-b545-47c6-8da5-b72180d9d060
Source identifiers:
179375
Local pid:
pubs:179375

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