- Abstract:
-
Background: Germline mutations in the PALB2 gene are associated with the genetic disorder Fanconi anaemia and increased predisposition to cancer. Disease-associated variants are mainly protein-truncating mutations, whereas a few missense substitutions are reported to perturb its interaction with breast canc...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted manuscript
- Files:
-
-
(pdf, 4.1mb)
-
- Publisher copy:
- 10.12688/wellcomeopenres.13113.1
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- Publisher:
- F1000Research Publisher's website
- Journal:
- Wellcome Open Research Journal website
- Volume:
- 2
- Issue:
- 110
- Publication date:
- 2017-11-14
- Acceptance date:
- 2017-11-10
- DOI:
- ISSN:
-
2398-502X
- Pubs id:
-
pubs:744816
- URN:
-
uri:6d8f1bd2-f59e-4429-9791-6f520e1937db
- UUID:
-
uuid:6d8f1bd2-f59e-4429-9791-6f520e1937db
- Local pid:
- pubs:744816
- Copyright holder:
- © 2017 Bleuyard JY et al.
- Copyright date:
- 2017
- Notes:
- This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Journal article
Perturbation of PALB2 function by the T413S mutation found in small cell lung cancer
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