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Journal article

Immediate transfusion in African children with uncomplicated severe anemia

Abstract:

BACKGROUND

The World Health Organization recommends not performing transfusions in African children hospitalized for uncomplicated severe anemia (hemoglobin level of 4 to 6 g per deciliter and no signs of clinical severity). However, high mortality and readmission rates suggest that less restrictive transfusion strategies might improve outcomes.


METHODS

In this factorial, open-label, randomized, controlled trial, we assigned Ugandan and Malawian children 2 months...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1056/NEJMoa1900105

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
ORCID:
0000-0002-0412-8509

Contributors

Role:
Contributor
Publisher:
Massachusetts Medical Society Publisher's website
Journal:
New England Journal of Medicine Journal website
Volume:
381
Issue:
5
Pages:
407-419
Publication date:
2019-08-01
Acceptance date:
2019-05-21
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
Source identifiers:
1011520
Pubs id:
pubs:1011520
UUID:
uuid:6d846421-cfde-4285-b19a-c2c93d5b92c2
Local pid:
pubs:1011520
Deposit date:
2019-06-11

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