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Journal article : Review

Model membrane systems to reconstitute immune cell signaling

Abstract:

Understanding the broad variety of functions encoded in cellular membranes requires experimental systems mimicking both their biochemical composition and biophysical properties. Here, we review the interplay between membrane components and the physical properties of the plasma membrane worth considering for biomimetic studies. Later, we discuss the main advantages and caveats of different model membrane systems. We further expand on how the use of model systems has contributed to the understa...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/febs.15488

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
ORCID:
0000-0003-4983-6389
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM - Investigative Medicine Division
Role:
Author
ORCID:
0000-0002-4915-388X
More from this funder
Name:
Wellcome Trust
Grant:
100262/Z/12/Z
More from this funder
Name:
Kennedy Institute of Rheumatology Trust
Grant:
MSP12 13 21
Publisher:
Wiley
Journal:
FEBS Journal More from this journal
Volume:
288
Issue:
4
Pages:
1070-1090
Place of publication:
England
Publication date:
2020-08-03
Acceptance date:
2020-07-14
DOI:
EISSN:
1742-4658
ISSN:
1742-464X
Pmid:
32681663
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1122747
Local pid:
pubs:1122747
Deposit date:
2020-08-12

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