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Characterization of full-length hepatitis C virus sequences for subtypes 1e, 1h and 1l, and a novel variant revealed Cameroon as an area in origin for genotype 1.

Abstract:

In this study, we characterized the full-length genome sequences of seven hepatitis C virus (HCV) isolates belonging to genotype 1. These represent the first complete genomes for HCV subtypes 1e, 1h, 1l, plus one novel variant that qualifies for a new but unassigned subtype. The genomes were characterized using 19-22 overlapping fragments. Each was 9400-9439 nt long and contained a single ORF encoding 3019-3020 amino acids. All viruses were isolated in the sera of seven patients residing in, ...

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Publication status:
Published

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Publisher copy:
10.1099/vir.0.048835-0

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Journal:
Journal of general virology More from this journal
Volume:
94
Issue:
Pt 8
Pages:
1780-1790
Publication date:
2013-08-01
DOI:
EISSN:
1465-2099
ISSN:
0022-1317
Language:
English
Keywords:
Pubs id:
pubs:401157
UUID:
uuid:6d63e1ee-a03a-467b-a920-a922c7c0a9fd
Local pid:
pubs:401157
Source identifiers:
401157
Deposit date:
2013-11-16

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