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Journal article

Evidence for loss of a partial flagellar glycolytic pathway during trypanosomatid evolution

Abstract:

Classically viewed as a cytosolic pathway, glycolysis is increasingly recognized as a metabolic pathway exhibiting surprisingly wide-ranging variations in compartmentalization within eukaryotic cells. Trypanosomatid parasites provide an extreme view of glycolytic enzyme compartmentalization as several glycolytic enzymes are found exclusively in peroxisomes. Here, we characterize Trypanosoma brucei flagellar proteins resembling glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and phosphoglycer...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0103026

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS ONE Journal website
Volume:
9
Issue:
7
Pages:
ARTN e103026
Publication date:
2014-07-22
Acceptance date:
2014-06-27
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Source identifiers:
477704
Language:
English
Keywords:
UUID:
uuid:6d5c20f6-c8f6-4948-9f4b-6acf87f05f5c
Local pid:
pubs:477704
Deposit date:
2014-08-11

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