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Primary causes of decreased mitochondrial oxygen consumption during metabolic depression in snail cells.

Abstract:

Cells isolated from the hepatopancreas of estivating snails (Helix aspersa) have strongly depressed mitochondrial respiration compared with controls. Mitochondrial respiration was divided into substrate oxidation (which produces the mitochondrial membrane potential) and ATP turnover and proton leak (which consume it). The activity of substrate oxidation (and probably ATP turnover) decreased, whereas the activity of proton leak remained constant in estivation. These primary changes resulted in...

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Publication status:
Published

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Publisher copy:
10.1152/ajpregu.00401.2001

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine
St-Pierre, J More by this author
Journal:
American journal of physiology. Regulatory, integrative and comparative physiology
Volume:
282
Issue:
2
Pages:
R372-R382
Publication date:
2002-02-05
DOI:
EISSN:
1522-1490
ISSN:
0363-6119
URN:
uuid:6d5b7b77-179d-48ab-bf62-494c5f81691d
Source identifiers:
347054
Local pid:
pubs:347054

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