- Abstract:
- In a randomised trial (ACST-1) of 3120 asymptomatic patients withsevere carotid narrowing comparing early with deferred carotid endarterectomy(CEA), CEA significantly reduced 10-year stroke risk. All other aspects ofpatient treatment were left to the discretion of the clinician. Throughout thetrial antithrombotic and antihypertensive drugs were widely used but use oflipid-lowering therapy increased substantially. We examined the influence ofdifferent medical treatments on the overall stroke prevention effect of the trial.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Publisher copy:
- 10.1002/bjs.7396
-
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- Publisher:
- Wiley Publisher's website
- Volume:
- 98
- Pages:
- 9-9
- Publication date:
- 2010-12-23
- DOI:
- EISSN:
-
1365-2168
- ISSN:
-
0007-1323
- URN:
-
uuid:6d461643-1e9a-4dae-8935-75962f4ed200
- Source identifiers:
-
252455
- Local pid:
- pubs:252455
- Copyright holder:
- British Journal of Surgery Society Ltd
- Copyright date:
- 2010
- Notes:
- © 2011 British Journal of Surgery Society Ltd. Published by John Wiley and Sons Ltd. The final version is available online from Wiley at: [10.1002/bjs.7396]
Conference
Combined medical therapy and carotid endarterectomy for asymptomatic stenosis: 10-year stroke prevention in ACST-1
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