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Journal article

Cerebral perfusion SPET correlated with Braak pathological stage in Alzheimer's disease.

Abstract:

Reductions in regional cerebral perfusion, particularly in the posterior temporo-parietal lobes, are well recognized in Alzheimer's disease. We set out to correlate perfusion changes, using (99m)Tc-HMPAO single photon emission tomography (SPET), with the pathological stage of Alzheimer's disease. The 'Braak stage' of the distribution of neurofibrillary pathology in post-mortem brains was used to classify SPET scans taken in life from a mixed (dementia and control) elderly population into the ...

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Publication status:
Published

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Publisher copy:
10.1093/brain/awf185

Authors


Bradley, KM More by this author
O'Sullivan, VT More by this author
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Journal:
Brain : a journal of neurology
Volume:
125
Issue:
Pt 8
Pages:
1772-1781
Publication date:
2002-08-05
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
URN:
uuid:6d30352b-21d3-4646-b44e-4f46f28d7156
Source identifiers:
195477
Local pid:
pubs:195477

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