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Canagliflozin, dapagliflozin and empagliflozin monotherapy for treating type 2 diabetes: systematic review and economic evaluation.

Abstract:

Background

Most people with type 2 diabetes are overweight, so initial treatment is aimed at reducing weight and increasing physical activity. Even modest weight loss can improve control of blood glucose. If drug treatment is necessary, the drug of first choice is metformin. However, some people cannot tolerate metformin, which causes diarrhoea in about 10%, and it cannot be used in people with renal impairment. This review appraises three of the newest class of drugs for monothe...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.3310/hta21020

Authors


Johnston, R More by this author
Cummins, E More by this author
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Grant:
Health Technology Assessment programme
Publisher:
NIHR Journals Library Publisher's website
Journal:
Health Technology Assessment Journal website
Volume:
21
Issue:
2
Pages:
1-218
Publication date:
2017-01-05
Acceptance date:
2016-06-01
DOI:
ISSN:
2046-4924
Pubs id:
pubs:675831
URN:
uri:6d2d7070-bd12-4c5e-b221-061c3b856667
UUID:
uuid:6d2d7070-bd12-4c5e-b221-061c3b856667
Local pid:
pubs:675831
Language:
English
Keywords:

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