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Can the density of native pancreatic tissue slices predict human islet isolation and purification outcome?

Abstract:

INTRODUCTION: With currently available technology, the outcomes of human islet isolation and purification are still inconsistent, in part due to a lack of control of the pancreas donor and the procurement conditions. Using a single donor pancreas, the critical islet mass for establishing insulin independence of approximately 5000 engrafted islet equivalents (IEQ)/kg of recipient weight can only be retrieved from about one third of isolations. The purpose of this study was to analyze whether s...

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
Journal:
Transplantation proceedings
Volume:
36
Issue:
9
Pages:
2845-2848
Publication date:
2004-11-05
DOI:
EISSN:
1873-2623
ISSN:
0041-1345
URN:
uuid:6d28f851-6c8e-40f3-8422-34db5222bc0a
Source identifiers:
255809
Local pid:
pubs:255809

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