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Operable non-small cell lung cancer: correlation of volumetric helical dynamic contrast-enhanced CT parameters with immunohistochemical markers of tumor hypoxia.

Abstract:

PURPOSE: To assess the relationship between helical dynamic contrast material-enhanced (DCE) computed tomographic (CT) parameters and immunohistochemical markers of hypoxia in patients with operable non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: After institutional review board approval was obtained, 20 prospective patients who were suspected of having NSCLC underwent whole-tumor DCE CT with kinetic modeling (Patlak analysis) 24 hours before scheduled surgery. Flow-extraction pro...

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Publisher copy:
10.1148/radiol.12111505

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Journal:
Radiology
Volume:
264
Issue:
2
Pages:
581-589
Publication date:
2012-08-01
DOI:
EISSN:
1527-1315
ISSN:
0033-8419
Source identifiers:
339887

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