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Journal article

Characterisation of the specificity, functionality and durability of host T-cell responses against the full-length hepatitis E virus

Abstract:

The interplay between host antiviral immunity and immunopathology during hepatitis E virus (HEV) infection determines important clinical outcomes. We characterized the specificity, functionality, and durability of host T‐cell responses against the full‐length HEV virus and assessed a novel “Quantiferon” assay for the rapid diagnosis of HEV infection. Eighty‐nine volunteers were recruited from Oxford, Truro (UK), and Toulouse (France), including 44 immune‐competent patients with acute HEV infe...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/hep.28819

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Publisher:
Wiley
Journal:
Hepatology More from this journal
Publication date:
2016-10-28
Acceptance date:
2016-08-17
DOI:
ISSN:
0270-9139 and 1527-3350
Pmid:
27631819
Language:
English
Keywords:
Pubs id:
pubs:644015
UUID:
uuid:6d1f7b88-5837-4fed-a61e-beaaa2ee2fe6
Local pid:
pubs:644015
Source identifiers:
644015
Deposit date:
2016-09-27

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