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Prostate cancer proteomics: The urgent need for clinically validated biomarkers

Abstract:

Prostate cancer (PCa) is the most common cancer diagnosis and the second most common cause of cancer-related deaths in men. Currently, serum prostate-specific antigen (PSA) is the only biomarker widely used in the diagnosis and management of patients with PCa. However, PSA lacks diagnostic sensitivity and specificity, leading to false-negative and false-positive test results. PSA cannot distinguish indolent from aggressive disease, leading to many patients being over-treated with associated s...

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Publication status:
Published

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Publisher copy:
10.1002/prca.200800154

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Journal:
PROTEOMICS CLINICAL APPLICATIONS More from this journal
Volume:
3
Issue:
2
Pages:
197-212
Publication date:
2009-02-01
DOI:
EISSN:
1862-8354
ISSN:
1862-8346
Language:
English
Keywords:
Pubs id:
pubs:120850
UUID:
uuid:6d1dd943-4666-4bce-8ccf-52ff22193ca4
Local pid:
pubs:120850
Source identifiers:
120850
Deposit date:
2012-12-19

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