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Journal article

Genetic pathways in colorectal cancer.

Abstract:

The model of colorectal tumorigenesis put forward by Fearon and Vogelstein has had great influence on molecular oncology. They proposed that a series of mutations occur in the progression from normal cells to colorectal cancer and that these mutations are associated with the histological features of such tumours. Several postulates of the model appear to be correct, particularly its emphasis on the stepwise accumulation of genetic changes and the inclusion of mutations at the adenomatous poly...

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Journal:
Histopathology More from this journal
Volume:
28
Issue:
5
Pages:
389-399
Publication date:
1996-05-01
DOI:
EISSN:
1365-2559
ISSN:
0309-0167
Language:
English
Keywords:
Pubs id:
pubs:72306
UUID:
uuid:6d155cf0-e70b-4a8b-84a2-c04c2a48d62c
Local pid:
pubs:72306
Source identifiers:
72306
Deposit date:
2012-12-19

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