Journal article
Expression of multiple catechol-o-methyltransferase (COMT) mRNA variants in human brain.
- Abstract:
-
Catechol-o-methyltransferase (COMT) is important for modulating dopamine levels, prefrontal cortex (PFC) function, and several psychiatric phenotypes. A single COMT mRNA has been described in human brain, which gives rise to membrane-bound (MB)- and soluble (S)-COMT proteins. In addition, we have recently described a novel COMT protein isoform in the human PFC, suggesting that there are more COMT gene products expressed than are currently appreciated. Therefore, we have investigated whether v...
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- Publication status:
- Published
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- Publisher copy:
- 10.1002/ajmg.b.30539
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Authors
Bibliographic Details
- Journal:
- American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
- Volume:
- 144B
- Issue:
- 6
- Pages:
- 834-839
- Publication date:
- 2007-09-01
- DOI:
- EISSN:
-
1552-485X
- ISSN:
-
1552-4841
- Source identifiers:
-
98022
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:98022
- UUID:
-
uuid:6d0c4dcd-dcac-4edd-bdba-0a4326aa303a
- Local pid:
- pubs:98022
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2007
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