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Journal article

C2028T polymorphism in exon 12 and dinucleotide repeat polymorphism in intron 13 of the HIF-1alpha gene define HIF-1alpha protein expression in non-small cell lung cancer.

Abstract:

OBJECTIVES: In this study, we investigated whether polymorphisms of the HIF-1alpha gene may account for the patterns of HIF-1alpha protein expression in non-small cell lung carcinomas (NSCLC) and the expression of HIF-1alpha down-stream proteins. METHODS: Specific HIF-1alpha polymorphisms were assessed in a series of patients with NSCLC: (a) the C to T transition at nucleotide 1744 (position 2028 according to sequence with accession number , which gives rise to Pro/Ser variation at codon 582...

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Publication status:
Published

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Journal:
Lung cancer (Amsterdam, Netherlands) More from this journal
Volume:
53
Issue:
3
Pages:
257-262
Publication date:
2006-09-01
DOI:
EISSN:
1872-8332
ISSN:
0169-5002
Language:
English
Keywords:
Pubs id:
pubs:119361
UUID:
uuid:6cfe4a58-7dbd-4f50-a76e-4a7a9754c7c3
Local pid:
pubs:119361
Source identifiers:
119361
Deposit date:
2012-12-19

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