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Journal article

Perfusion culture enhanced human endometrial stromal cell growth in alginate-multivalent integrin α5β1 ligand scaffolds.

Abstract:

A method to functionalize alginate by introducing monomeric or self-assembling (tetrameric) fibronectin (FN) domains is described, leading to a functional scaffold, which is used for three dimensional (3D) culture of human endometrial stromal cells (EnSCs). EnSCs encapsulated in the functional alginate were cultured under perfusion using the TissueFlex® platform, a multiple parallel microbioreactor system for 3D cell culture. The effect of the novel scaffold and the effect of perfusion were e...

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Publication status:
Published

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Publisher copy:
10.1002/jbm.a.33177

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Institution:
University of Oxford
Department:
Oxford, MPLS, Engineering Science
Role:
Author
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Journal:
Journal of biomedical materials research. Part A
Volume:
99
Issue:
2
Pages:
211-220
Publication date:
2011-11-05
DOI:
EISSN:
1552-4965
ISSN:
1549-3296
URN:
uuid:6cfdb3ae-1b3c-4352-9bb2-1999a9b62ad9
Source identifiers:
186246
Local pid:
pubs:186246

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