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Antibodies in melioidosis: the role of the indirect hemagglutination assay in evaluating patients and exposed populations

Abstract:

Melioidosis is a major neglected tropical disease with high mortality, caused by the Gram-negative bacterium Burkholderia pseudomallei (Bp). Microbiological culture remains the gold standard for diagnosis, but a simpler and more readily available test such as an antibody assay is highly desirable. In this study, we conducted a serological survey of blood donors (n = 1,060) and adult melioidosis patients (n = 200) in northeast Thailand to measure the antibody response to Bp using the indirect ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.4269/ajtmh.17-0998

Authors


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Institution:
University of Oxford
Division:
SE-Other
Department:
External
Role:
Author
ORCID:
0000-0002-8395-6037
More from this funder
Funding agency for:
Dunachie, S
Grant:
WT100174/Z/12/Z
Publisher:
American Society of Tropical Medicine and Hygiene Publisher's website
Journal:
American Journal of Tropical Medicine and Hygiene Journal website
Volume:
99
Issue:
6
Pages:
1378 - 1385
Publication date:
2018-10-08
Acceptance date:
2018-08-22
DOI:
EISSN:
1476-1645
ISSN:
0002-9637
Pmid:
30298810
Language:
English
Keywords:
Pubs id:
pubs:927164
UUID:
uuid:6cf76011-3193-477a-941c-3956ac4bbec6
Local pid:
pubs:927164
Source identifiers:
927164
Deposit date:
2018-11-14

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