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Journal article

Electrophysiology of pancreatic β-cells in intact mouse islets of Langerhans.

Abstract:

When exposed to intermediate glucose concentrations (6-16 mol/l), pancreatic β-cells in intact islets generate bursts of action potentials (superimposed on depolarised plateaux) separated by repolarised electrically silent intervals. First described more than 40 years ago, these oscillations have continued to intrigue β-cell electrophysiologists. To date, most studies of β-cell ion channels have been performed on isolated cells maintained in tissue culture (that do not burst). Here we will re...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
Journal:
Progress in biophysics and molecular biology More from this journal
Volume:
107
Issue:
2
Pages:
224-235
Publication date:
2011-11-01
DOI:
EISSN:
1873-1732
ISSN:
0079-6107
Language:
English
Keywords:
Pubs id:
pubs:166444
UUID:
uuid:6ce91d58-0fe7-471f-86ba-7e79d4533411
Local pid:
pubs:166444
Source identifiers:
166444
Deposit date:
2012-12-19

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