Journal article
Lovastatin for the treatment of adult patients with dengue: A randomized, double-blind, placebo-controlled trial.
- Abstract:
-
Background
Dengue endangers billions of people in the tropical world, yet no therapeutic is currently available. In part, the severe manifestations of dengue reflect inflammatory processes affecting the vascular endothelium. In addition to lipid lowering, statins have pleiotropic effects that improve endothelial function, and epidemiological studies suggest that outcomes from a range of acute inflammatory syndromes are improved in patients already on statin therapy.
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Clinical Infectious Diseases Journal website
- Volume:
- 62
- Issue:
- 4
- Pages:
- 468-476
- Publication date:
- 2016-02-01
- Acceptance date:
- 2015-10-29
- DOI:
- EISSN:
-
1537-6591
- ISSN:
-
1058-4838
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:588864
- UUID:
-
uuid:6ce32f0a-3b79-4d5a-8215-1615d562906d
- Local pid:
- pubs:588864
- Source identifiers:
-
588864
- Deposit date:
- 2016-02-18
Terms of use
- Copyright holder:
- Whitehorn et al
- Copyright date:
- 2016
- Notes:
- © The Author 2015. Published by Oxford University Press for the Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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