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Thesis

The three-dimensional regulatory landscapes of the globin genes

Abstract:

One of the most important outstanding questions in biology involves the precise spatial and temporal regulation of gene activity, which enables different cell types to express the specific set of genes required for their function and is therefore a cornerstone for complex biological life. Cis-regulatory elements, such as gene promoters and enhancers, play a key role in controlling gene activity. These elements physically interact with the genes they regulate within structural chro...

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Division:
MSD
Role:
Author

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Supervisor
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Supervisor
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Funding agency for:
Oudelaar, A
Grant:
105281/Z/14/Z
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
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UUID:
uuid:6cd793fe-b28a-4d98-a588-b6eec5dfa416
Deposit date:
2018-11-01

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